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2022-2023 Andre Berndt, PhD, Assistant Professor, Department of Bioengineering, University of Washington Massively parallel, high throughput engineering of optogenetic biosensors for neuronal signaling Florescent, genetically encoded proteins have revolutionized the study of brain cells and neural circuits. By literally lighting up in the presence of specific neural activity, which then can be recorded by microscopes …

2020-2022 Ehud Isacoff, Ph.D., Evan Rauch Chair, Department of Neuroscience, University of California, Berkeley Dirk Trauner, Ph.D. Janice Cutler Chair in Chemistry and Adjunct Professor of Neuroscience and Physiology, New York University Photo-activation of Dopamine Receptors in Models of Parkinson's Disease Dopamine is generally known for its association with creating positive sensations or for its …

2025-2027 Arkarup Banerjee, Ph.D., Assistant Professor, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY Neural Circuit Mechanisms for Behavior Novelty The origins of diverse behavioral traits have fascinated biologists for centuries. Many studies have identified genetic pathways that influence animal behavior, but the neural circuit basis of how complex behaviors evolve, especially in mammals, remains …

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Aligned Investments Aligned investments are in harmony with the McKnight Foundation’s mission and values. Their financial performance is evaluated against the broader market. High Impact Investments High impact investments deliver greater environmental and social change. Most have market expectations; a few Program-Related Investments have charitable expectations. Exited Investments Exited investments are no longer in our …