Guddiga Agaasimayaasha Sanduuqa Dhaqaalaha ee McKnight for Neuroscience ayaa ku faraxsan inay ku dhawaaqaan inay doorteen lix neurosaariyiin si ay u helaan abaalmarinta 2018 McKnight Scholar.
Abaalmarinta McKnight Scholar waxaa la siiyaa saynisyahanno dhallinyaro ah oo ku jira marxaladaha ugu horeeya ee abuura shaybaarro madaxbannaan oo madax banaan iyo cilmi-baarisyo kuwaas oo muujiyay ballanqaad ku saabsan neuroscience. "Hadafka Sanduuqa Maaliyad-bixinta waa in la taageero cilmi-baaris cusub oo cilmi-baaris cusub oo cilmi-baaris ah oo cilmi-nafsi ah u keeni karto maalinta maalinta cudurada maskaxda lagu xaqiijin karo, looga hortagi karo, laguna daaweyn lahaa," ayuu yidhi Kelsey C. Martin MD, oo ah guddoomiyaha guddiga abaalmarinta iyo Daahir ka mid ah David Geffen School of Medicine ee UCLA. Tan iyo markii abaalmarinta la soo saaray 1977, abaal-marintan prestigious ee hore ee xirfadeed ayaa maal-galisay in ka badan 225 baarayaal cusub oo soo bandhigay boqolaal muuqaal oo muuqaal ah.
"Cilmi-baarista sanadkaan ee McKnight Scholars ayaa waxay ka dhigan tahay mawduucyada aasaasiga ah ee unugyada unugyada jirka ee miyir-qabka ee horumarinta iyo cudurada mabaadi'da aasaasiga ah ee ururada wareega ee dabeecadaha adag," ayuu yiri Martin. "Waxyaabaha halbeegga ah ee lixda ka mid ah shahaadooyinka da'da yar ee dhiirigeliya dhalinyarada waa inay ka fekeraan sanduuqa si ay u keenaan naqshado, farsamo, qadarin, iyo habab cusub oo looga hortago caqabadaha iyagoo ka jawaabaya su'aalaha waqti dheer ee neurosiyaanka. Anigoo ku hadlaya magaca guddida oo idil, waxaan jeclaan lahaa inaan u mahadceliyo dhammaan codsadayaasha loogu talagalay abaalmarinta "McKnight Scholar Awards" ee ku aaddan rajo-gelinta iyo kalsoonida mustaqbalka neeriga. "
Mid kasta oo ka mid ah lixda qof ee qaata abaalmarinta "McKnight Scholar Award" waxay heli doonaan $ 75,000 sanadkiiba muddo saddex sano ah. Waxay yihiin:
| Eiman Azim, Ph.D. Machadka Salk La Jolla, CA |
Xakameynta Spinal Circuits Xakamaynta Dhaqdhaqaaqa Dhibcaha ah |
| Rudy Behnia, Ph.D. Jaamacadda Columbia New York, NY |
Nuuromodulation-ku-dawlad-ku-tiirsanaanta Himilada Miisaanka |
| Felice Dunn Ph.D. Jaamacadda California, San Francisco San Francisco, CA |
Hirgalinta iyo Xeer-dejinta Aragga iyo Qalabka Cose |
| John Tuthill Ph.D. Jaamacadda Washington Seattle, WA |
Xakamaynta Macaamilka ee Meel-marinta Meel-marinta ee Drosophila |
| Mingshan Xue, Ph.D. Baylor College of Medicine Houston, TX |
Farsamaynta iyo Mashruuca Nidaamka Muusigga ah ee Qalabaynta Qalalaasaha Qalabka ah ee Vostostatic In Vivo |
| Brad Zuchero, Ph.D. Jaamacadda Stanford Palo Alto, CA |
Mechanisms of Myelin Membrane Kobaca iyo Wareejinta |
Waxaa jiray 64 qof oo codsadey abaalmarinta "McKnight Scholar Awards", oo matalaya macalimiinta ugu wanaagsan dhalinyarada maskaxda ee dhalinyarada. Iskuulka dhalinyaradu waxay xaq u leeyihiin abaalmarinta afartii sano ee ugu horreysey ee jaamacadda. Marka laga reebo Martin, guddiga xulashada jaamacada waxaa ka mid ah Dora Angelaki, Ph.D., Baylor College of Medicine; Loren Frank, Ph.D., Jaamacadda California, San Francisco; Richard Mooney, Ph.D., Duke University School of Medicine; Anthony Movshon, Ph.D., New York University School of Medicine; Amita Sehgal, Ph.D., Jaamacadda Pennsylvania Medical School; iyo Michael Shadlen, MD, Ph.D., Columbia University.
Codsiyada abaalmarinta sannadka soo socda ayaa la heli doonaa bisha Sebtembar waxaana la filayaa bilowga Jeenawari 2019. Wixii macluumaad dheeraad ah ee ku saabsan barnaamijyada abaalmarinta qalqaalada McKnight, fadlan booqo bogga internetka ee Sanduuqa Dhaqaalaha https://www.mcknight.org/programs/the-mcknight-endowment-fund-for-neuroscience
Ku saabsan Sanduuqa Maaliyadda ee McKnight Fund for Neuroscience
Sanduuqa McKnight Fund ee Neuroscience waa urur madax-bannaan oo keliya oo ay maalgeliso Hay'adda McKnight Foundation ee Minneapolis, Minnesota waxaana hoggaaminaya guddi khubaro ah oo ku takhasusay neurosuusyada ka socda waddanka. Machadka McKnight Foundation wuxuu taageersanaa cilmi baarista neurosiyaanka tan iyo 1977-kii. Foundation wuxuu aasaasay Sanduuqa Maaliyadda ee 1986 si uu u fuliyo mid ka mid ah rabitaanka aasaasaha aasaasaha aasaasaha aasaasaha William L. McKnight (1887-1979). Mid ka mid ah hoggaamiyayaashii ugu horeeyay ee shirkadda 3M, wuxuu lahaa dareen shakhsi ah oo xasuusta iyo cudurrada maskaxda waxayna doonayaan qayb ka mid ah dhaxalka uu u adeegsaday si uu u helo daaweynta. Sanduuqa Maalgashiga (Funding Endowment) wuxuu sameeyaa sadex nooc oo abaalmarin ah sannad kasta. Marka laga soo tago Abaalmarinta Ardayda McKnight, waxay yihiin McKnight Technological Innovations ee Abaalmarinta Neuroscience, bixinta lacagta abuurka si loo hormariyo khubaro farsamo si kor loogu qaado cilmi-baarista maskaxda; iyo McKnight Memory and Cognitive Disorders Awards for scientists ka shaqeynaya si ay u adeegsadaan aqoonta lagu gaarey iyada oo loo marayo cilmi-baaris aasaasiga ah si ay cudurada maskaxda ee saameyn ku xasuusta xasuusta ama garashada.
2018 McKnight Scholar Awards
Eiman Azim, Ph.D., Kaaliyaha Professor, Shaybaarka Naasnuujiyaha Naasnuujiyeynta,
Machadka Salk ee Daraasaadka Bayoolojiga, La Jolla, CA
Xakameynta Spinal Circuits Xakamaynta Dhaqdhaqaaqa Dhibcaha ah
Dhaqdhaqaaqa adag ee gacmaheenna, gacmaheena iyo faraha ayaa aasaas u ah isdhexgalka maalinlaha ah ee adduunka, laakiin sayniska ayaa kaliya bilaabaya in uu xoqo dareenka fahamka sida xuubka neerfaha ee qaaska ah u xakameynayo saxda, xawaaraha iyo daacadnimada dabeecadahan kartida leh. Dr. Azim oo ah shaybaarka machadka Salk wuxuu ku yaalaa horudhaca arimahan, isaga oo dejinaya habab badan oo kala duwan oo loola jeedo in la naqshadeeyo kala duwanaanshaha maadooyinka, anatomical iyo hawlaha kala duwan ee wadooyinka mootooyinka hal mar. Ka faa'iideysiga horumarka dhawaan ee barashada mashiinka, teknoolajiyada aragtida kombuyuutarka iyo qalabka molecular-genetic, Azim Lab ayaa ujeedkiisu yahay in la horumariyo habab badan oo siman, oo aan si daacad ah lahayn, si sare loogu qaadayo si loo wada dhimo dhaqdhaqaaqa maskaxda ee dhaqdhaqaaqa - gaar ahaan dhaqdhaqaaqyo xirfad leh sida goolka la taaban karo iyo qabashada. Natiijooyinkoodu waxay caawin karayaan in la caddeeyo sida cudur ama dhaawac u gooyey fulinta dhaqdhaqaaqa caadiga ah ee dhaqdhaqaaqa, taas oo ka dhigaysa habka loogu talagalay ogaanshaha xanuunka iyo daaweynta.
Rudy Behnia, Ph.D., Kaaliyaha Professor of Neuroscience, Columbia University-Zuckerman Mind Behind Behavior Institute, New York, NY
Nuuromodulation-ku-dawlad-ku-tiirsanaanta Himilada Miisaanka
Dr. Behnia waxa uu barayaa hababka firfircoon ee loo hindisay aragtida, sahaminta habka muuqaalka ee maskaxda ee ku dhaqma dabeecadaha waxayna caawisaa xayawaanka iyo bini-aadanka inay ku noolaadaan oo ku raaxaystaan jawiyada adag ee lagu hayo dareenka dareenka. Iyadoo la adeegsanayo nidaamka moodada miro-hawleedka, shaybaadhka Behnia wuxuu baaraa sida xayawaanku u arkaan oo u waafajiyo habdhaqankooda bedelida jawi iyada oo loo marayo farsamooyin kala duwan, oo ay ka mid yihiin gudaheeda hal sawir oo kabaro ah oo isku-xiran, laba sawir-qaadasho-sawir, farsamoyaqaan iyo dabeecadaha habdhaqanka. Doodda gaarka ah ee Dr. Behnia ee shaqada laga maalgaliyo McKnight wuxuu raadin doonaa sida dawladaha gudaha ah sida dareenka wax ka baddelaya dareenka maskaxda ee dareenka qaarkood, cilmi baaris ah oo daadi kara iftiinka cusub ee doorka neuromodululatorka ee ciyaaraya beddelidda shaqada wareegyada neuralada. Cilmi baaristani waxay sidoo kale muujin kartaa bartilmaameedyo cusub oo loogu talagalay xeeladaha daaweynta ee xanuunada sida niyad jabka iyo ADHD.
Felice Dunn, Ph.D., Kaaliyaha Professor of Ophthalmology, University of California, San Francisco
Hirgalinta iyo Xeer-dejinta Aragga iyo Qalabka Cose
Cilmi-baadhistii Dr. Dunn waxa uu diiradda saarayaa sidii loo ogaan lahaa sida muuqaalka macluumaadka muuqaalkiisa loo xakameeyay oo laga baaraandego wareegga retina, aqoonta u furi karta jidadka cusub ee dib u soo celinta aragtida lumay. Inkasta oo cudurro badan oo retinal ah oo keena luminta aragga ama indho la'aantu ay ka bilaabmayso xumaynta fotoreceptors, sida cudurku u socdo inuu saameyn ku yeesho qanjirrada postsynaptic weli lama yaqaan. Dumarkeeda, Dunn waxay gashaa xayeysiinta transgenic ee wareega wareega ee fotoreceptors, duubista farsamada iyo sawiridda unugyada hal, iyo hababka gene-editing si ay u baaraan unugyada haray ee unugyada iyo synptses. Shaqadeeda waxay kaa caawin doontaa in la ogaado sida wareegga soo hadhay uu bedelo qaab-dhismeedkiisa iyo shaqadiisa ku-oolka ah ee xasaasiga ah, waxaana laga yaabaa in uu gacan ka geysto muujinta daaweynta suurtagalka ah ee la joojiyo ama looga hortago aragti la'aanta.
John Tuthill, Ph.D., Kaaliyaha Professor, Physiology iyo Biophysics, Jaamacadda Washington, Seattle
Xakamaynta Macaamilka ee Meel-marinta Meel-marinta ee Drosophila
Mabaadi'da-dareenka jireed ee is-dhaqdhaqaaqa iyo isbeddelka-wuxuu muhiim u yahay, xakamaynta dhaqdhaqaaqa dhaqdhaqaaqa, weli wax yar ayaa laga ogyahay sida ay u socoto wareegyada wareega ee maskaxda si ay ula socdaan dhaqdhaqaaqa mustaqbalka. Dr. Tuthill's labadaba wuxuu ka shaqeynayaa inuu furo nuxurka barashada mashiinka maskaxda adoo baaraya sida duurjoogta miraha lugta leh ay bartaan in ay ka hortagaan caqabadaha oo ay ku socdaan jawi aan la saadaalin Karin, oo qiimeynaya doorka dareemaha dareenka ee maareynta maareynta iyada oo si sahlan loo adeegsado dhaqdhaqaaqa. Fahamka qoto dheer ee ku saabsan xakameynta jawaab celinta ee suurtogalka ah ayaa suurtagal ah in la bedelo habka aan u fahamno uguna daaweyno xanuunada dhaqdhaqaaqa.
Mingshan Xue, Ph.D., Kaaliyaha Professor, Baylor College of Medicine, Houston, TX
Farsamaynta iyo Mashruuca Nidaamka Muusigga ah ee Qalabaynta Qalalaasaha Qalabka ah ee Vostostatic In Vivo
Hagaajinta agagaaraha adag iyo bedelida waddamada gudaha, maskaxda caafimaadku waxay xajisaa isku dheelitir joogto ah oo u dhexeeya kacsanaanta iyo ka hortagga (inta badan lagu tilmaamo sida saamiga E / I) taas oo si aad ah ugu xasilloon. Sidee ayay maskaxdu u joogtaa miisaankan? Dr. Xue's laboratory wuxuu sahmin doonaa su'aashan, isku duba ridida molecular, genetic, electrophysiological, optogenetic, sawirada, iyo hababka anatomical si loo go'aamiyo in balaastigga caadiga ah uu nidaamiyo jajabyada habka gaarka ah ee kudhaca jiilka, taas oo ilaalineysa heerarka dhaqdhaqaaqa neuronal iyo guryaha wax ka qabashada. Qaadashada faham qoto dheer oo ah sida maskaxda caadiga ah ay ufudud u yeelato xannibaadaha ayaa xoojin karta habka loogu talagalay in lagu daaweeyo cudurada dareemayaasha ee khalkhalka dabiiciga ah ee maskaxda.
Brad Zuchero, Ph.D., Kaaliyaha Professor of Neurosurgery, Jaamacadda Stanford, Palo Alto, CA
Mechanisms of Myelin Membrane Kobaca iyo Wareejinta
Maqnaanshaha myelin - insulatorka korontada ee dusha sare ee qulqulka neuronal-wuxuu keeni karaa awood daran iyo garaadka garaadka ee bukaanka qaba sclerosis badan iyo cudurrada kale ee nidaamka dareenka dhexe. In la dhiso "habdhismeedka buugta" ee qaababka istiraatiijiga ah ee xoojiya abuurista myelin hada waa hadafka Dr. Zuchero ee shaybaadhka cilmibaadhista ee Jaamacadda Stanford. Isku-dubbaridka habab cusub oo ay ku jiraan microscopy-xallinta qiyaasta, genome-keeda CRISPR / Cas, iyo qalabka cytoskeletal ee novel-ka ee lagu sameeyay shaybaarkiisa, kooxda Zuchero ayaa baaraya sida iyo sababta finanku ay u baahan yihiin si xun u kala jajabnaanta ficilka oligodendrocyte actin cytoskelton, waxay muujinaysaa bartilmaameed cusub ama jidad daweyn ah oo loogu talagalay dib-u-dhiska iyo dayactirka.
